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Implications of immune function to anesthesia care

Charles A Griffis1, Gayle Page, Michael Kremer

  • 1University of California, Los Angeles, Department of Anesthesiology, USA. cgriffis@mednet.ucla.edu

AANA Journal
|December 19, 2008
PubMed

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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