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Updated: Jun 27, 2026
A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
Published on: May 4, 2021
Oxygen inhalation using an oxygen concentrator in a low-pressure environment outside of a hospital
Hirokazu Sakaue1, Takashi Suto, Masafumi Kimura
1Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
Abstract:
Supplementation with oxygen is fundamental in rescue and emergency medicine. However, transportation of oxygen cylinders or a rigid hyperbaric chamber requires large work forces. Also, oxygen in a cylinder may be completely consumed during a rescue action. The oxygen concentrators, which enrich the oxygen percentage of ambient air, may free rescuers from carrying heavy oxygen cylinders. In the present study, 2 types of oxygen concentrators were tested in a mountain hut located at an altitude of 3776 m. Oxygen concentration of the generated gas was 28.6% +/- 0.8% with the first machine, which was powered by an internal battery. Arterial oxygen saturation of the volunteers inhaling through the machine increased from the original 79% +/- 6% to 82% +/- 6%. When the machine was used with a semi-closed circuit, the value increased further to 90% +/- 3%. The second concentrator, which was powered by an external electric generator, outputted 90% +/- 2% oxygen. Arterial oxygen saturation of the volunteers increased to 95% +/- 1%. It is concluded that both types of oxygen concentrators were efficient at high altitude.
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