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Frankincense: systematic review.
1Complementary Medicine, Peninsula Medical School, Universities of Exeter and Plymouth, Exeter EX2 4NT, UK. edzard.ernst@pms.ac.uk
Evidence from randomized clinical trials suggests Boswellia serrata (frankincense) extracts are effective for various conditions. While encouraging, more compelling research is needed to confirm the clinical efficacy of frankincense extracts.
Area of Science:
- Pharmacology and Therapeutics
- Evidence-Based Medicine
Background:
- Boswellia serrata, commonly known as frankincense, has a long history of traditional use.
- Scientific investigation into its therapeutic potential is ongoing.
Purpose of the Study:
- To systematically review randomized clinical trials (RCTs) evaluating the effectiveness of Boswellia serrata extracts.
- To assess the quality of evidence for Boswellia serrata in various medical conditions.
Main Methods:
- A systematic review of RCTs was conducted.
- Searches included major databases (Medline, Embase, etc.) and hand searches.
- Studies were selected based on inclusion criteria, and methodological quality was assessed using the Jadad score.
Main Results:
- Seven RCTs met the inclusion criteria, covering asthma, rheumatoid arthritis, Crohn's disease, osteoarthritis, and collagenous colitis.
- All included trials indicated clinical effectiveness of Boswellia serrata extracts.
- Three studies demonstrated good methodological quality, with no significant safety concerns reported.
Conclusions:
- The current evidence suggests Boswellia serrata extracts show promise as a therapeutic agent.
- The existing data is encouraging but not yet compelling enough to make definitive conclusions.
- Further high-quality research is warranted to solidify the role of frankincense in clinical practice.
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