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Related Concept Videos

Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Mutagenicity and Carcinogenicity01:25

Mutagenicity and Carcinogenicity

Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for Research on Cancer (IARC) classifies agents into four groups based on their carcinogenic potential. Group 1 agents are known human carcinogens; group 2A agents are probably carcinogenic to humans; group 3 agents lack data to support their role in carcinogenesis; and group 4 includes agents for which data support that they are not likely to be...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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Such genes that act...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Tumor Progression02:07

Tumor Progression

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Related Experiment Video

Updated: Jun 27, 2026

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer
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A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

Published on: July 6, 2017

Carcinoid tumors.

Scott N Pinchot1, Kyle Holen, Rebecca S Sippel

  • 1Section of Endocrine Surgery, Department of Surgery, University of Wisconsin, Madison, WI 53792, USA.

The Oncologist
|December 19, 2008
PubMed
Summary
This summary is machine-generated.

Carcinoid tumors, rare neuroendocrine neoplasms, present diagnostic and therapeutic challenges. A multidisciplinary approach is crucial for accurate diagnosis and effective management of these slow-growing tumors.

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Area of Science:

  • Oncology
  • Pathology
  • Medical Imaging

Background:

  • Carcinoid tumors are rare, slow-growing neuroendocrine neoplasms originating from enterochromaffin cells.
  • They are found in the gastrointestinal and bronchopulmonary systems.
  • Traditional classification is evolving due to significant clinical and histopathologic variability.

Purpose of the Study:

  • To highlight the diagnostic challenges posed by carcinoid tumors.
  • To emphasize the necessity of a multidisciplinary approach in diagnosis and treatment.
  • To discuss the prognostic factors influencing patient outcomes.

Main Methods:

  • Biochemical analysis
  • Standard cross-sectional imaging (e.g., CT, MRI)
  • Nuclear medicine advancements (e.g., PET scans)

Main Results:

  • Carcinoid tumors often appear innocuous at presentation, complicating early diagnosis.
  • A combination of imaging, biochemical tests, and nuclear medicine is essential for diagnosis.
  • Surgery is the only curative treatment option for primary and disseminated disease.

Conclusions:

  • Carcinoid tumors require a comprehensive, multidisciplinary diagnostic and treatment strategy.
  • Prognosis is variable, depending on tumor location, metastatic extent, and diagnostic timing.
  • Ongoing research into classification and diagnostic tools is vital for improving patient care.