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Updated: Jun 27, 2026

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
Published on: September 12, 2016
Acute demyelinating disorders of the central nervous system
Abstract:
Acute demyelinating disorders of the central nervous system represent some of the most formidable management and therapeutic challenges to clinicians. These disorders include acute relapses of multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis, optic neuritis, and transverse myelitis. This paper summarizes clinical manifestations of these disorders, as well as treatment strategies. Currently, immunosuppression with corticosteroids for the acute events is the mainstay of treatment. Other experimental therapies, which may be effective in certain patients, are discussed.
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