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Published on: October 20, 2017
Vertebral artery dissection: natural history, clinical features and therapeutic considerations
Kwan-Woong Park1, Jong-Sun Park, Sun-Chul Hwang
1Department of Neurosurgery, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
Insights
Vertebral artery dissection (VAD) involves a tear in major neck arteries, leading to stroke in young adults. This review covers VAD
Area of Science:
- Neurology
- Vascular Surgery
- Cardiovascular Research
Background:
- Cervicocerebral artery tears cause vessel stenosis or aneurysms.
- Vertebral artery dissection (VAD) is a rare but significant cause of stroke in young, healthy individuals.
Purpose of the Study:
- To review recent advancements in understanding vertebral artery dissection (VAD).
- To cover epidemiology, pathogenesis, clinical features, diagnosis, and treatment of VAD.
Main Methods:
- Literature review of recent developments in VAD research.
- Synthesis of information on VAD epidemiology and pathogenesis.
- Compilation of data on clinical manifestations, diagnosis, and treatment.
Main Results:
- VAD is a primary cause of stroke in younger populations.
- Understanding of VAD's occurrence and development has advanced.
- Diverse clinical presentations and diagnostic methods exist for VAD.
Conclusions:
- VAD requires continued research for improved understanding and patient outcomes.
- Early diagnosis and appropriate treatment are crucial for managing VAD.
- Further investigation into VAD pathogenesis may reveal novel therapeutic targets.
Abstract:
When a tear occurs in one of the major cervicocerebral arteries and allows blood to enter the wall of the artery and split its layers, the result is either stenosis or aneurysmal dilatation of the vessel. Vertebral artery dissection (VAD) is an infrequent occurrence but is a leading cause of stroke in young and otherwise healthy patients. This article discusses recent developments in understanding of the epidemiology and pathogenesis of VAD and the various clinical manifestations, methods of diagnosis, and approaches to treatment.
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