[Ten years' experience at a major stroke center]

T Konatschnig1, A Knöll, A Hug

  • 1Neurologische Klinik der Ruprecht Karls-Universität Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Deutschland. Thomas.Konatschnig@med.uni-heidelberg.de

Der Nervenarzt
|December 23, 2008
PubMed

Insights

Reducing prehospital delay significantly increased the number of stroke patients eligible for acute intravenous thrombolysis. This improvement was achieved without changes in patient demographics or stroke severity over a decade.

Area of Science:

  • Neurology
  • Public Health

Background:

  • 1,300 stroke patients treated annually at University Hospital Heidelberg.
  • Data collected prospectively from 1996-2006.
  • Focus on changes in patient population and thrombolysis suitability.

Purpose of the Study:

  • Analyze changes in stroke patient demographics and treatment from 1996 to 2006.
  • Evaluate the impact of prehospital delay on intravenous thrombolysis eligibility.
  • Assess trends in acute stroke care.

Main Methods:

  • Retrospective analysis of prospectively collected patient data.
  • Inclusion of basic demographic and clinical data (age, sex, stroke type, NIH Stroke Scale).
  • Detailed data on prehospital and in-hospital delays, and thrombolysis treatment parameters.

Main Results:

  • No significant changes in total stroke patient numbers or median stroke severity (NIH Stroke Scale) from 1996 to 2006.
  • Proportion of patients arriving within 3 hours of symptom onset increased from 12.1% to 21.9%.
  • Intravenous thrombolysis treatment increased to 10.1% of ischemic stroke patients, representing 39% of those with cerebral infarction arriving within the critical 3-hour window.

Conclusions:

  • Sociodemographic data of stroke patients remained stable during the study period.
  • Consistent reduction in prehospital delay was key to increasing the number of patients receiving acute intravenous thrombolysis.
  • Improved patient flow and timely intervention enhance acute stroke treatment outcomes.
Abstract

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