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Updated: Jun 27, 2026

Analysis of Chromosome Segregation, Histone Acetylation, and Spindle Morphology in Horse Oocytes
Published on: May 11, 2017
Dynamic changes of germinal vesicle chromatin configuration and transcriptional activity during maturation of rabbit
Hui-Li Wang1, Hong-Shu Sui, Yong Liu
1College of Animal Science & Veterinary Medicine, Shandong Agricultural University, Tai-an City, People's Republic of China.
Abstract:
Dynamic changes in configuration of germinal vesicle (GV) chromatin and their effects on oocyte transcriptional activity and developmental competence were studied in rabbit oocytes. The results indicated that global condensation of GV chromatin, rather than the formation of a perinucleolar ring, would better reflect the global transcriptional repression and developmental competence of oocytes. Gonadotropins, by promoting large-scale chromatin remodeling, regulate oocyte transcriptional activity and developmental competence.
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