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Related Experiment Videos

Issues in implementing clinical research in nursing home settings.

J S Eisch, J Colling, J Ouslander

    The Journal of the New York State Nurses' Association
    |September 1, 1991
    PubMed
    Summary

    Researchers faced challenges obtaining informed consent from frail, cognitively impaired nursing home residents for urinary incontinence clinical trials. Strategies were developed to overcome these research barriers and implement individualized toileting prescriptions.

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    Area of Science:

    • Gerontology
    • Clinical Nursing Research
    • Health Services Research

    Background:

    • Conducting clinical trials in nursing home settings presents unique challenges.
    • Frail, cognitively impaired populations require specific considerations for informed consent.
    • Urinary incontinence is a prevalent issue in long-term care facilities.

    Purpose of the Study:

    • To describe the informed consent and institutional barriers encountered in a multi-site nursing home study.
    • To outline successful strategies for overcoming these barriers in research with vulnerable populations.
    • To implement and evaluate an individualized toileting prescription for urinary incontinence.

    Main Methods:

    • A collaborative, quasi-experimental, two-year clinical trial was conducted across four geographically diverse nursing home sites.

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  • The study involved close collaboration with indigenous nursing and nurse aide staff.
  • An individualized toileting prescription was implemented as the independent variable.
  • Main Results:

    • Consistent problems in the informed consent process were identified across all sites.
    • Similar institutional barriers hindered research progression.
    • Effective strategies were developed and utilized to surmount these research obstacles.

    Conclusions:

    • Implementing clinical trials in nursing homes requires addressing specific ethical and logistical challenges.
    • Successful research in this setting depends on collaborative partnerships with facility staff.
    • The study provides valuable insights into overcoming barriers for research involving frail, cognitively impaired individuals.