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Updated: Jun 26, 2026

Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection
Published on: November 7, 2018
[Genotypes of hepatitis B virus in Henan Luohe area]
Fu-Qing Wang1, Xiao-Lei Huang, Ai-Qin Li
1Luohe Medical College, Luohe 462002, China.
Objective:
To determine the main genotype of hepatitis B virus (HBV) prevailed in Henan Luohe area.
Methods:
Serum specimens were collected from 94 HBsAg positive individuals, and HBV S gene were obtained by PCR amplifying, and the gene sequences were analyzed and the polygenetic tree was drawn by the software MEGA3.
Results:
About 75.7% samples of HBV S gene clustered in genotype C, about 20% samples clustered at genotype B in the HBV polygenetic tree, about 4.3% samples clustered at genotype D in the HBV polygenetic tree.
Conclusion:
The main genotype of hepatitis B virus prevalent in Henan Luohe is genotype C, genotype B is rarely seen, and genotype D is rarely seen.
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