Related Experiment Video
Updated: Jun 26, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
Published on: April 9, 2014
Drug-drug interactions with newer antiretroviral agents
1New York University School of Medicine and Bellevue Hospital Center, New York, NY, USA.
Abstract:
Knowledge of drug interactions among antiretroviral agents and other drugs used by HIV-infected patients is essential to maintaining safety and efficacy of drug treatment. Often, the clinical impact of drug-drug interactions cannot be predicted on the basis of pharmacokinetic interactions alone, highlighting the need for studies and analyses that provide exposure-response data. Drug interactions in HIV-infected patients can be complex and sometimes counterintuitive, and practitioners must increasingly rely on a concerted approach to gathering information on drug interactions that goes beyond studies showing exposure changes for coadministered drugs.
More Related Videos
Related Concept Videos
Pharmacokinetics: Drug–Food and Drug–Viral Interactions
Pharmacokinetics: Drug–Drug Interactions
Antiviral Nucleoside Inhibitors
Drug toxicity: Drug–Drug Interaction
Retrovirus Life Cycles
Inhibitors of Viral Protein Synthesis

