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Updated: Jun 26, 2026
07:02
Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
Published on: September 14, 2010
Malignancies in HIV: the Indian scenario
Aruna Alahari Dhir1, Sheela P Sawant
1Department of Medicine, Tata Memorial Hospital, Parel, Mumbai, India. arunaalahari@hotmail.com
Current Opinion in Oncology
|December 25, 2008
Summary
India has a high number of HIV/AIDS patients, with non-Hodgkin's lymphoma and cervical cancer being more common. Further research is needed to understand the full burden of HIV-related cancers in India.
Area of Science:
- Oncology
- Infectious Diseases
- Public Health
Background:
- India has the second-highest number of individuals living with HIV/AIDS globally.
- Limited research exists on HIV-related malignancies within the Indian population.
- Increased life expectancy due to antiretroviral therapy may lead to a rise in these cancers.
Purpose of the Study:
- To review the current landscape of HIV-related malignancies in India.
- To highlight the specific cancer types and their prevalence in HIV-infected individuals in India.
Main Methods:
- Literature review of existing studies on HIV/AIDS and cancer in India.
- Analysis of reported cancer incidence in HIV-positive versus HIV-negative populations in India.
Main Results:
- Non-Hodgkin's lymphoma and cervical cancer show higher incidence in HIV-infected individuals in India.
- AIDS-defining cancers like primary CNS lymphoma and Kaposi's sarcoma are less common in India.
- Increased frequency of anal, testicular, Hodgkin's disease, colon, head and neck cancers (men), and vaginal cancers (women) observed.
Conclusions:
- Antiretroviral therapy may increase future mortality and morbidity from neoplastic diseases in HIV patients.
- Large-scale, collaborative studies are essential to accurately assess the burden of HIV-related malignancies across India's diverse regions.
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