Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

When all is said and done....

B Benacerraf1

  • 1Department of Pathology, Harvard Medical School, Boston, Massachusetts.

Annual Review of Immunology
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

This review details key immunology discoveries, including immune complex diseases and T-cell specificity. It highlights the role of MHC molecules in antigen presentation and explores the maturation of antibody responses.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nobel laureates' letter to President Bush.

The Washington post·2002
Same author

Three-dimensional prenatal diagnosis of frontonasal malformation and unilateral cleft lip/palate.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2002
Same author

Isolated major congenital heart disease.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2001
Same author

Variation in fetal femur length with respect to maternal race.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine·2001
Same author

Isolated polydactyly: prenatal diagnosis and perinatal outcome.

Prenatal diagnosis·2000
Same author

The prognostic significance of hyperextension of the fetal head detected antenatally with ultrasound.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2000
Same journal

The Neuroimmune Circuitry of Peripheral Sensory Neuron Subtypes in Chronic Pain.

Annual review of immunology·2026
Same journal

The Spectrum of Fibroblast Immune Biology.

Annual review of immunology·2026
Same journal

The Molecular Logic of Immunoglobulin Heavy Chain Class Switch Recombination.

Annual review of immunology·2026
Same journal

Decoding Human T Cell Immunity with Artificial Intelligence and Single-Cell Genomics.

Annual review of immunology·2026
Same journal

Immune Niches in Cancer.

Annual review of immunology·2026
Same journal

T Cell Receptor Signaling and Immune Tolerance: From Autoimmunity to Cancer Immunity.

Annual review of immunology·2026
See all related articles

Area of Science:

  • Immunology and Molecular Biology
  • Cellular Biology
  • Immunogenetics

Background:

  • Review of over 30 years of immunological research and training.
  • Exploration of the phagocytic activity of the reticulo-endothelial system.
  • Analysis of the pathogenesis of immune complex diseases.

Discussion:

  • Impact of activated macrophages on tumor rejection.
  • Evidence for T-cell immunity specificity for processed internal protein determinants.
  • Maturation of antibody response, focusing on antibody affinity.

Key Insights:

  • Discovery of Ir gene control over specific immune responses.
  • Elucidation of the role of Major Histocompatibility Complex (MHC) molecules in presenting peptide antigens to T cells.

Related Experiment Videos

  • Understanding the generation of alloreactivity.

    • Outlook:

    • Discussion on the administration of science.
    • Challenges in technology transfer to industrial partners.
    • Future directions in immunological research and application.