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Updated: Jun 26, 2026
OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery
Published on: May 9, 2021
Comparison of in vitro fertilization versus intracytoplasmic sperm injection in extremely low oocyte retrieval cycles
Yu-Che Ou1, Kuo-Chung Lan, Fu-Jen Huang
1Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Niaosung Hsiang, Kaohsiung, Taiwan.
Objective:
To compare the results of IVF and intracytoplasmic sperm injection (ICSI) in extremely low oocyte retrieval cycles.
Design:
Case-control study.
Setting:
An IVF laboratory in a university hospital in Taiwan.
Patient(S):
Between January 2003 and December 2007, infertile couples with one, two, or three oocytes per retrieval were divided into two groups: 56 IVF cycles based on 28 demographic characteristics from the ICSI group.
Intervention(S):
None.
Main Outcome Measure(S):
Fertilization rate, cycle cancellation rate, clinical pregnancy rate, and implantation rate per transfer.
Result(S):
The normal fertilization rate was significantly higher after ICSI than after standard IVF (86.4% vs. 69.3%). The cycle cancellation and complete fertilization failure rates were comparable between the two groups. The clinical pregnancy rate per transfer (38.5% vs. 21.6%), implantation rate (23.5% vs. 11.1%), and live birth rate per transfer (30.8% vs. 13.7%) had a favorable trend, but no statistically significant differences, in the ICSI group compared with the IVF group.
Conclusion(S):
A higher normal fertilization rate can be achieved by ICSI in comparison with conventional IVF in extremely low oocyte retrieval cycles.
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