[Hemodynamic changes in an acute pancreatitis experimental model in awaken rats]

The aim of the present study was to determine the hemodynamic effect of acute hemorrhagic pancreatitis in conscious rats. For this purpose, radioactive microspheres were used in 3 groups: control (n = 5); 25 min pancreatitis (n = 10); 50 min pancreatitis (n = 10), performing a basal and final (25 or 50 minutes postpancreatitis) hemodynamic study. Acute hemorrhagic pancreatitis was induced in 25 min and 50 min pancreatitis groups overwhelming shock with decrease of 55% in cardiac output, 58% in renal blood flow while total peripheral resistance increased in 342%. No changes were registered the in control group.