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Related Concept Videos

Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Plant Breeding and Biotechnology01:59

Plant Breeding and Biotechnology

Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
Incomplete Dominance01:43

Incomplete Dominance

Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.

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Updated: Jun 26, 2026

Breeding by Design for Functional Rice with Genome Editing Technologies
09:43

Breeding by Design for Functional Rice with Genome Editing Technologies

Published on: January 3, 2025

Economic evaluation of genomic breeding programs.

S König1, H Simianer, A Willam

  • 1Institute of Animal Breeding and Genetics, University of Göttingen, 37075 Göttingen, Germany. skoenig2@gwdg.de

Journal of Dairy Science
|December 26, 2008
PubMed
Summary
This summary is machine-generated.

Genomic breeding programs offer significant economic advantages over conventional dairy cattle breeding, primarily by reducing generation intervals. These programs are most effective when at least 20% of inseminations use genotyped young bulls without waiting for daughter records.

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Area of Science:

  • Animal Breeding and Genetics
  • Agricultural Economics
  • Quantitative Genetics

Background:

  • Conventional dairy cattle breeding relies on progeny testing, which involves long generation intervals.
  • Genomic selection offers potential for faster genetic gain but requires accurate genomic indices and cost-effective implementation.
  • Economic viability is a key factor in adopting new breeding technologies in dairy farming.

Purpose of the Study:

  • To compare the economic efficiency of conventional progeny testing with various genomic breeding program scenarios.
  • To evaluate the impact of factors like genotyping costs, selection intensity, and farmer adoption rates on genomic breeding success.
  • To determine the conditions under which genomic breeding programs outperform traditional methods in dairy cattle.

Main Methods:

  • A deterministic model using gene flow and selection index calculations was employed.
  • Modeled scenarios included variations in genotyping costs, selection intensity, and farmer reliance on daughter records.
  • Technical and biological coefficients specific to a German breeding organization were utilized.

Main Results:

  • Genomic breeding programs showed a distinct economic advantage (up to 2.59 times higher discounted profit) when genomic index accuracies exceeded 0.70.
  • Genotyping costs were found to be negligible from a population-wide perspective.
  • Higher discounted profits were achieved in genomic scenarios with at least 20% of inseminations by genotyped young bulls without daughter records.

Conclusions:

  • Genomic breeding programs are economically superior to conventional progeny testing, especially when progeny testing is fully abandoned.
  • The success of genomic breeding hinges on farmer willingness to adopt genotyped young bulls without waiting for daughter performance data.
  • Genomic selection enables substantial genetic gain for both low and moderately heritable traits with highly accurate genomic indices.