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Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
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Information learned from animal models of atrial fibrillation

J Emanuel Finet1, David S Rosenbaum, J Kevin Donahue

  • 1The Heart and Vascular Research Center, Case Western Reserve University, MetroHealth Campus, 2500 MetroHealth Drive, Cleveland, OH 44109-1998, USA.

Cardiology Clinics
|December 30, 2008
PubMed

Keywords:
cardiac arrhythmiaexperimental cardiologyheart rhythm disordertranslational research

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Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.