Related Experiment Video
Updated: Jun 26, 2026

11:27
Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
Renal cell carcinoma in a child
Mehdi Salehipour1, Alireza Rasekhi, Mohammad Vasei
1Department of Urology, Shiraz University of Medical Sciences, Shiraz, Iran. Salehipour@sums.ac.ir
Summary
Pediatric renal cell carcinoma is rare, with no established treatment guidelines. This case highlights an unusual presentation of this uncommon childhood cancer.
Area of Science:
- Pediatric Oncology
- Urology
- Rare Cancers
Background:
- Renal cell carcinoma (RCC) is exceptionally rare in pediatric populations, accounting for less than 2% of all childhood cancers.
- Current management strategies lack standardized treatment protocols for pediatric RCC, posing challenges for oncologists and urologists.
- The rarity and unique biological behavior of pediatric RCC necessitate further investigation into its characteristics and optimal therapeutic approaches.
Observation:
- This report details a specific case of renal cell carcinoma in a child.
- The patient presented with an atypical clinical manifestation of the disease.
- The uncommon presentation underscores the diagnostic and therapeutic complexities associated with pediatric renal tumors.
Findings:
- The case illustrates a non-standard clinical course for a pediatric renal cell carcinoma.
- Diagnostic and management challenges were encountered due to the unusual presentation.
- This case contributes to the limited body of knowledge on rare pediatric malignancies.
Implications:
- Highlights the need for increased awareness and research into pediatric renal cell carcinoma.
- Suggests the importance of considering diverse presentations when diagnosing rare childhood cancers.
- Emphasizes the potential need for developing tailored treatment protocols for pediatric RCC based on case studies and further research.
Related Concept Videos
The Retinoblastoma Gene
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The Retinoblastoma Gene
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Rous Sarcoma Virus (RSV) and Cancer
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
