[Parameters of enzyme reactions in microcirculation]
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Updated: Oct 31, 2026

The ex vivo Isolated Skeletal Microvessel Preparation for Investigation of Vascular Reactivity
Published on: April 28, 2012
Abstract:
It has been shown that time-dependent change in the concentration of enzymic reaction substrate in a microcirculatory channel cell, as well as its steady spatial distribution contain information both about the structure of the microcirculatory channel and about the reaction kinetic parameters. In terms of the hypothesis about the stationary state of the enzyme-substrate complex at selective values of hydrodynamic parameters of the substrate, enzyme, channel correlation between the change in the substrate concentration, its stationary distribution, kinetic parameters and the microcirculation cell structure were estimated.
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