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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
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A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...

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Updated: Jun 26, 2026

Routine Screening Method for Microparticles in Platelet Transfusions
09:49

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Published on: January 31, 2018

[Indications for platelet transfusion].

Dalia Adukauskiene1, Aida Kinderyte, Audrone Veikutiene

  • 1Department of Intensive Care, Kaunas University of Medicine, Eiveniu 2, Kaunas, Lithuania. daliaadu@gmail.com

Medicina (Kaunas, Lithuania)
|January 7, 2009
PubMed
Summary

Platelet transfusions are crucial for managing bleeding risks in thrombocytopenia. Proper use reduces hospital stays for critically ill patients, with specific dose recommendations and effectiveness evaluations post-transfusion.

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Last Updated: Jun 26, 2026

Routine Screening Method for Microparticles in Platelet Transfusions
09:49

Routine Screening Method for Microparticles in Platelet Transfusions

Published on: January 31, 2018

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
09:38

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

Area of Science:

  • Hematology
  • Transfusion Medicine
  • Critical Care Medicine

Background:

  • Platelet transfusions are increasingly indicated for hemorrhage risk, despite a lack of standardized protocols.
  • Thrombocytopenia in critically ill patients correlates with extended intensive care unit (ICU) and hospital stays.
  • High costs associated with platelet transfusion necessitate appropriate usage guidelines.

Purpose of the Study:

  • To review the relevance and recommendations for platelet transfusion.
  • To discuss the impact of appropriate platelet use on patient outcomes.
  • To present the advantages of different platelet transfusion doses.

Main Methods:

  • Review of existing literature and professional consensus recommendations from 2003.
  • Consideration of factors beyond platelet count, such as critical conditions influencing bleeding risk.
  • Evaluation of platelet transfusion effectiveness at various time points.

Main Results:

  • Platelet count recommendations include a minimum of 55 x 10(9)/L per dose to achieve a 5-10 x 10(9)/L increase.
  • Effectiveness is assessed 10-60 minutes, 18 hours, and 24 hours post-transfusion.
  • Critical conditions like trauma and head injury increase bleeding risk and influence transfusion decisions.

Conclusions:

  • Appropriate platelet transfusion is vital for reducing thrombocytopenia and improving outcomes in critically ill patients.
  • Adherence to recommended platelet counts and consideration of clinical context enhance transfusion efficacy.
  • Further research into optimal transfusion strategies and dose-response relationships is warranted.