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Related Concept Videos

Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.

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Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
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Fourmidable: a database for ant genomics.

Yannick Wurm1, Paolo Uva, Frédéric Ricci

  • 1Department of Ecology and Evolution, Biophore, University of Lausanne, Lausanne, Switzerland. yannick.wurm@unil.ch

BMC Genomics
|January 8, 2009
PubMed
Summary
This summary is machine-generated.

Fourmidable is a new database for ant genetic and genomic data. It provides access to expressed sequence tag (EST) and gene expression data for ants, aiding research in ant genomics.

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Area of Science:

  • Genomics
  • Bioinformatics
  • Entomology

Background:

  • Emerging genetic, molecular, and functional genomic data for ants require robust curation and sharing infrastructure.
  • Ants are a diverse and ecologically significant insect group, yet genomic resources are fragmented.

Purpose of the Study:

  • To establish Fourmidable, an infrastructure for curating and disseminating ant genomic data and protocols.
  • To provide a searchable and scalable database for ant genetic information.

Main Methods:

  • The Fourmidable assembly pipeline clusters nucleotide sequences for independent assembly.
  • Annotation is performed using Interproscan and BLAST against general and insect-specific databases.
  • Data retrieval is facilitated through gene identifiers, sequence similarity searches, and Gene Ontology annotations.

Main Results:

  • Fourmidable currently contains expressed sequence tag (EST) data from two ant species.
  • Microarray gene expression data is available for one of these ant species.
  • The database is designed for scalability with increasing sequence data and species.

Conclusions:

  • Fourmidable offers a centralized resource for ant genomic data, including EST and gene expression data.
  • The infrastructure supports data sharing and retrieval, advancing ant research.
  • Fourmidable is publicly accessible at http://fourmidable.unil.ch.