Related Experiment Video
Updated: Jun 26, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Does a system of instalment dispensing for newly prescribed medicines save NHS costs? Results from a feasibility
John Millar1, Paul McNamee, David Heaney
1Dingwall Medical Group-Health Centre, Ferry Road, Dingwall, Ross-Shire, UK. jsmdingwall@hotmail.com
Background:
In view of the increasing cost of general practice of drug prescribing, it is important to look at ways of reducing drug wastage and thereby improve the cost-effectiveness of prescribing.
Objective:
To determine the costs and cost savings to the NHS of instalment dispensing for newly prescribed medicines and to quantify the extra costs incurred by patients.
Methods:
Patients were randomized to receive either a normal (n = 103) or an instalment (n = 101) prescription.
Results:
The difference between prescribed and dispensed drug costs in the intervention group was 0.98 UK pounds per patient (95% confidence interval 0.14-1.82 UK pounds), giving a 7% reduction in drug costs. The costs of the additional pharmacy time required to implement the intervention was calculated to be 5.02 UK pounds per patient.
Conclusions:
Introduction of a system of instalment dispensing produced savings in the general practice of drugs bill, but these were not large enough to offset additional costs for pharmacists.
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