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Deafness associated with acetaminophen and codeine abuse.

Brian W Blakley¹, Heather Schilling

¹Department of Otolaryngology, University of Manitoba, Winnipeg, Manitoba. bblakley@exchange.hsc.mb.ca

Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'Oto-Rhino-Laryngologie Et De Chirurgie Cervico-Faciale

|January 9, 2009

Summary

This summary is machine-generated.

Ototoxicity, or hearing loss, can result from narcotic-acetaminophen combinations. Patients experiencing unexplained hearing loss should be questioned about their use of these common over-the-counter medications.

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Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity

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Published on: March 16, 2018

Area of Science:

Otolaryngology
Pharmacology
Toxicology

Background:

Narcotic-acetaminophen combinations are widely used for pain relief.
The ototoxic potential of these combinations is not commonly recognized by patients or healthcare providers.

Observation:

Progressive hearing loss of unknown etiology may be linked to the overuse of these medications.
Patients often perceive over-the-counter medications containing acetaminophen and a narcotic as safe.

Findings:

Ototoxicity, manifesting as severe-to-profound hearing loss, can be an overlooked consequence of these drug combinations.
A high index of suspicion is warranted in patients with unexplained hearing loss.

Implications:

Otolaryngologists should inquire about the use of acetaminophen and narcotic-containing medications in patients with unexplained hearing loss.
Increased awareness of this potential side effect is crucial for early diagnosis and intervention.
This highlights the importance of comprehensive medication history in audiological evaluations.