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Updated: Jun 26, 2026

Murine Excisional Wound Healing Model and Histological Morphometric Wound Analysis
Published on: August 21, 2020
Cell proliferation induction: healing chronic wounds through low-energy pulsed radiofrequency
Robert Frykberg1, Edward Tierney, Arthur Tallis
1Carl T. Hayden VA Medical Center, Phoenix, Arizona 85268, USA. Robert.frykberg@va.gov
Abstract:
Chronic lower extremity wounds are a major source of morbidity and health care expenditure across the world. In the last decade, numerous advanced modalities have become available that can help expedite wound healing when standard wound care modalities are unsuccessful. In this case report, the authors present their early experience with one such modality that uses pulsed radiofrequency energy to initiate cell proliferation induction in chronic lower extremity wounds of different etiologies that had failed to respond to standard therapy.
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