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Related Concept Videos

Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

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Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory...
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Updated: May 5, 2026

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Minimally Invasive Floating Metatarsal Osteotomy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis.

Arthur Tarricone1, Collin E Pehde1, Lee C Rogers1

  • 1Department of Orthopaedics, University of Texas at San Antonio, San Antonio, Texas, USA.

Wound Repair and Regeneration : Official Publication of the Wound Healing Society [And] the European Tissue Repair Society
|January 10, 2026
PubMed
Summary

Minimally invasive floating metatarsal osteotomy effectively treats diabetic foot ulcers (DFUs) with a 98% healing rate. This surgical approach offers rapid closure and low recurrence, making it a promising option for DFU management.

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Area of Science:

  • Orthopedic Surgery
  • Podiatric Medicine
  • Diabetic Foot Care

Background:

  • Diabetic foot ulcers (DFUs) pose a significant challenge due to underlying biomechanical deformities.
  • Recurrent or persistent DFUs often require advanced surgical interventions.

Purpose of the Study:

  • To systematically review and meta-analyze the efficacy of minimally invasive floating metatarsal osteotomy for neuropathic DFUs.
  • To evaluate healing rates, time to closure, and complication rates associated with the procedure.

Main Methods:

  • Systematic review and meta-analysis following PRISMA guidelines.
  • Searched four databases for studies on adult patients with neuropathic DFUs treated with minimally invasive floating metatarsal osteotomy.
  • Included studies with a minimum follow-up of 12 months.

Main Results:

  • Pooled analysis of six studies (184 subjects) showed a 98% DFU healing rate.
  • Mean time to closure was 31.7 days; ulcer recurrence was 4%.
  • Complication rates included transfer lesions (14%), nonunion (14%), and infection (7%).

Conclusions:

  • Minimally invasive floating metatarsal osteotomy is a safe and effective surgical option for off-loading neuropathic DFUs.
  • The procedure demonstrates high healing rates and rapid closure compared to conservative treatments.
  • Further randomized controlled trials are needed to validate findings and standardize indications.