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Neuro-endocrine cells--a new prognostic parameter in prostate cancer
R J Cohen1, G Glezerson, Z Haffejee
1Department of Anatomical Pathology, University of the Witwatersrand, Johannesburg, South Africa.
British Journal of Urology
|September 1, 1991
Abstract:
Neuro-endocrine cells are a recognised component of prostatic ducts and acini. Half of all clinically manifest cancers show neuro-endocrine differentiation. Occult carcinomas have a lower incidence of such differentiation. Neuro-endocrine cells are of major prognostic importance and appear more reliable in predicting patients' survival than do conventional histological grading systems.