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Updated: Jun 26, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Collagen embolization for the successful treatment of a distal coronary artery perforation
Godfrey Aleong1, Pilar Jimenez-Quevedo, Fernando Alfonso
1Interventional Cardiology Unit, Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain.
Insights
A man experienced coronary artery perforation during a procedure. Collagen embolization was successfully used for the first time to treat this rare complication.
Area of Science:
- Interventional Cardiology
- Vascular Surgery
Background:
- Coronary artery perforation is a rare but serious complication during percutaneous coronary interventions.
- Hydrophilic guidewires are commonly used but can increase the risk of vessel injury.
Observation:
- A 42-year-old male patient developed a right coronary artery perforation during a procedure involving a hydrophilic guidewire.
Findings:
- This case report details the first successful use of collagen embolization to manage coronary artery perforation.
- The collagen embolization technique provided an effective and minimally invasive solution to the arterial tear.
Implications:
- Collagen embolization represents a novel and promising therapeutic option for managing coronary artery perforation.
- This approach may reduce the need for more invasive surgical interventions in similar cases.
Abstract:
A 42-year old man suffered a coronary artery perforation in the right coronary artery secondary to a hydrophilic guidewire. We describe for the first time the use of collagen embolization to successfully treat this complication.
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