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Related Concept Videos

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Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Related Experiment Video

Updated: Jun 26, 2026

Picrosirius Red Staining for Semiquantitative Histopathologic Evaluation of Collagen Deposition in Murine Models of Chronic Lung Allograft Rejection
04:42

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Published on: March 21, 2025

Reactive perforating collagenosis.

Mukesh Kumar Yadav1, B C Sangal, Puneet Bhargav

  • 1Department of Pathology, SMS Medical College, Jaipur, India. dr_mukesh77@rediffmail.com

Indian Journal of Pathology & Microbiology
|January 13, 2009
PubMed
Summary

Reactive perforating collagenosis is a rare skin condition. This case study details acquired reactive perforating collagenosis in a patient with diabetes and chronic kidney disease.

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Last Updated: Jun 26, 2026

Picrosirius Red Staining for Semiquantitative Histopathologic Evaluation of Collagen Deposition in Murine Models of Chronic Lung Allograft Rejection
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Published on: May 23, 2025

Area of Science:

  • Dermatology
  • Nephrology
  • Endocrinology

Background:

  • Reactive perforating collagenosis (RPC) is a rare genodermatosis.
  • Its etiology remains largely unknown, presenting a diagnostic challenge.

Observation:

  • A case of acquired RPC was observed in a patient with diabetes mellitus and chronic renal failure.
  • The patient presented with characteristic skin lesions associated with these comorbidities.

Findings:

  • The study highlights a potential association between RPC and underlying conditions like diabetes and chronic kidney disease.
  • This case contributes to understanding acquired forms of RPC.

Implications:

  • This case underscores the importance of considering RPC in patients with diabetes and chronic renal failure.
  • Further research into the etiology of acquired RPC is warranted to improve patient management.