A novel HLA-Cw*0436 allele identified by haplotype-specific extraction and sequence-based typing
1Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Tissue Antigens
|January 15, 2009
Abstract:
A novel HLA-Cw*04 variant allele, Cw*0436, was identified in three members of a Korean family. This allele shows only one nucleotide difference from Cw*0411 in exon 2 at nucleotide position 268 (codon 90 GCC-->GAC), resulting in an amino acid change from Alanine (A) to Aspartic acid (D).
