Related Experiment Video
Updated: Jun 26, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Multislice computed tomographic findings in symptomatic patients after amplatzer septal occluder device implantation
Ali N Zaidi1, John P Cheatham, Subha V Raman
1Department of Internal Medicine, Division of Cardiovascular Medicine, The Ross Heart Hospital, The Ohio State University, Columbus, Ohio, USA.
Insights
Multislice computed tomography (MSCT) is feasible for assessing Amplatzer Septal Occluder (ASO) devices in patients experiencing symptoms after atrial septal defect (ASD) closure. This imaging technique provides detailed anatomical insights, aiding in the investigation of post-procedural complications.
Area of Science:
- Cardiology
- Medical Imaging
- Interventional Cardiology
Background:
- Transcatheter closure of atrial septal defects (ASDs) can lead to complications like pericardial effusion and tamponade.
- Transthoracic echocardiography in adults often has limitations due to poor acoustic windows, hindering complete device assessment.
- Multislice computed tomography (MSCT) offers an alternative imaging modality for evaluating the Amplatzer Septal Occluder (ASO) device anatomy.
Purpose of the Study:
- To determine the feasibility of using MSCT for anatomical assessment in patients with persistent or recurrent symptoms after transcatheter ASD closure with ASO devices.
Main Methods:
- Retrospective analysis of adult patients who underwent ASO implantation and subsequent MSCT imaging due to symptoms.
- Data collected included patient demographics, ASO device size, device-to-structure relationship, symptoms, and time from implantation to symptom onset.
Main Results:
- Eleven patients (mean age 41) with symptoms 1 week to 2.4 years post-implantation were analyzed.
- MSCT provided detailed anatomical information on device location relative to surrounding structures in all cases.
- Pericardial effusions were noted in two patients; one had nonobstructive coronary plaque.
Conclusions:
- Cardiac symptoms post-ASO implantation warrant thorough investigation.
- MSCT is a feasible and valuable tool for assessing ASO devices and their relationship to surrounding anatomy in symptomatic patients.
- MSCT should be considered an adjunct to echocardiography for evaluating symptomatic patients after ASO placement.
Background:
Complications of transcatheter closure of atrial septal defects (ASDs) include pericardial effusion, tamponade, and even death. Transthoracic echocardiography in the adult is often limited by poor acoustic windows that lead to incomplete device assessment. Advances in multislice computed tomography (MSCT) provide an alternative modality to assess the anatomy of the Amplatzer Septal Occluder (ASO) device.
Objective:
The purpose of this study was to determine the feasibility of MSCT in providing anatomic information in patients with persistent or recurrent symptoms after transcatheter closure of ASDs with ASO devices.
Methods:
A retrospective analysis of adult patients who underwent ASO device implantation with subsequent MSCT imaging as a result of symptoms from June 2006 to May 2007 was performed. Data analysis included age, gender, size of ASO device, relationship of the device to surrounding structures, symptoms, and the length of time between device implantation and onset of symptoms.
Results:
Eleven patients were identified with a mean age of 41 years. Patients presented with symptoms 1 week to 2.4 years after implantation. ASO size ranged from 8 to 36 mm. MSCT provided detailed information in all 11 cases regarding anatomic location of the device with respect to surrounding structures. Nonobstructive coronary plaque disease was identified in one patient. Two patients had pericardial effusions.
Conclusions:
Cardiac symptoms after ASO implant deserve thorough investigation. MSCT is feasible in the assessment of such patients and offers a unique assessment of the device to surrounding anatomic structures and should be considered as a useful adjunct to echocardiography in symptomatic patients.
Related Concept Videos
Mitral Stenosis II: Clinical features and Diagnostic Tests
Imaging Studies for Cardiovascular System V: CT
Acute Coronary Syndrome III: Diagnostic Studies

