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Updated: Jun 26, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
[Problem and strategy in surgical treatment of single ventricle]
1Department of Cardiovascular Surgery, First Hospital of Tsinghua University, Beijing 100016, China. wuqingyu@mail.tsinghua.edu.cn
Insights
Single ventricle disease, a complex congenital heart defect, benefits from surgical advancements. Optimal patient selection and management of pulmonary vascular resistance are crucial for successful surgical outcomes.
Area of Science:
- Congenital Heart Surgery
- Pediatric Cardiology
- Cardiovascular Physiology
Context:
- Single ventricle disease presents significant surgical challenges and high mortality.
- Recent advancements have improved surgical treatments, yet diagnostic and therapeutic issues persist.
Purpose:
- To review the concept, morphology, and pathophysiology of single ventricle disease.
- To discuss surgical techniques, including Fontan procedures and ventricular separation.
- To outline strategies for managing intraoperative and postoperative complications.
Summary:
- Extra-cardiac conduits enhance Fontan-type surgeries for single ventricle.
- Ventricular separation offers an alternative for select patients.
- Pulmonary artery development is promoted via systemic-to-pulmonary shunts for hypoplastic pulmonary vessels.
- Pulmonary artery banding manages pulmonary hypertension and prevents vascular changes.
Impact:
- Successful surgical outcomes depend on careful patient selection.
- Pulmonary vascular resistance and cardiac function are critical determinants of surgical success.
- Improved management strategies can reduce operative mortality in single ventricle patients.
Abstract:
Single ventricle disease is a complex congenital heart anomaly with a high operative mortality. In the past few years, much progress had been made in surgical treatment of single ventricle. However, some problems in the diagnosis and treatment still remained. Based on the author's experience, the concept, morphology, and pathophysiology were reviewed and indications of various surgical techniques, problems during the operation and post-operation with their strategies were discussed in this article. Most single ventricular diseases are treated by Fontan series surgery; in which better results can be achieved through extra-cardiac conduct. Ventricular separation which is better than Fontan series surgery can be performed on those qualified. If the pulmonary vessels are maldeveloped, systematic to pulmonary shunt is preferred to promote the development of pulmonary vessels. When pulmonary hypertension occurs, Banding procedure is suggested to prevent pathologic changes of pulmonary vessels. The development of pulmonary vessels and total pulmonary resistance varies greatly from patients at different ages. Choosing appropriate patients is the key to obtain satisfactory outcome.The pulmonary vessel resistance and cardiac function status are the most important factors for successful operation.
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