Related Experiment Video
Updated: Jun 26, 2026
07:37
An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
Published on: June 6, 2025
Biologic agents for rheumatoid arthritis: 2008 and beyond
Nadera J Sweiss1, Linda L Hushaw
1University of Chicago, Sarcoidosis and Scleroderma Clinic, Section of Rheumatology, Chicago, Illinois, USA.
Summary
New biologic drugs offer advanced rheumatoid arthritis (RA) treatment options. Nursing care is crucial for patient education and managing side effects of these novel therapies.
Area of Science:
- Immunology
- Rheumatology
- Pharmacology
Background:
- Rheumatoid arthritis (RA) is a chronic autoimmune disease with complex pathology.
- Patient presentation and disease progression in RA are highly variable.
- The therapeutic landscape for RA is evolving with the advent of novel treatments.
Purpose of the Study:
- To review emerging biologic disease-modifying antirheumatic drugs (DMARDs) for RA treatment.
- To highlight the role of nursing in managing patients on advanced RA therapies.
Main Methods:
- Review of late-stage clinical trial agents for RA.
- Identification of novel biologic DMARDs targeting specific inflammatory pathways.
Main Results:
- Several novel biologic agents are in late-stage development for RA.
- Key agents include anti-tumor necrosis factor (TNF)-alpha therapies (golimumab, certolizumab), an anti-CD20 agent (ocrelizumab), and an interleukin-6 inhibitor (tocilizumab).
Conclusions:
- Expanding RA treatment options necessitate enhanced nursing support.
- Patient education and adverse effect management are critical nursing interventions for optimizing outcomes with new RA biologics.
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