Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Role of Skin in Vitamin D Synthesis

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).

Connective Tissue Cell Types

Connective Tissue Cell Types

Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...

Role of Vitamins in Maintaining Bone Health

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...

Vitamins

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...

Essential Minerals for Bone Health

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...

Skeleton and Calcium Homeostasis

Skeleton and Calcium Homeostasis

Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Reducing therapeutic inertia in type 2 diabetes.

Australian journal of general practice·2024

Same author

An Overview of Appropriate Medical Practice and Preparedness in Radiation Emergency Response.

Cureus·2024

Same author

A case of multiple small red spots.

Australian journal of general practice·2022

Same author

Measurement of cumulative radiation exposure to children and adolescents in contact with outpatients treated with low dose radioactive iodine (<sup>131</sup>I).

Journal of the Egyptian National Cancer Institute·2020

Same author

Retrospective Study of Tc-99m Thyroid Scan in Patients with Graves' Disease: Is There Significant Difference in Lobar Activity?

Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India·2020

Same author

An unusual case of phytobezoar-induced small bowel obstruction.

Journal of surgical case reports·2019

Same journal

Occupational violence and staff safety in general practice.

Australian family physician·2018

Same journal

You should get that mole checked out: Ethical and legal considerations of the unsolicited clinical opinion.

Australian family physician·2018

Same journal

Understanding the decision to commence a dose administration aid.

Australian family physician·2018

Same journal

Psychological distress and risky sexual behaviours among women aged 16-25 years in Victoria, Australia.

Australian family physician·2018

Same journal

A mixed-methods feasibility study of routinely weighing patients in general practice to aid weight management.

Australian family physician·2018

Same journal

The Australian Mid-West Coastal Marine Wound Infections Study.

Australian family physician·2018

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Vitamin D - a review.

Mark L Stroud¹, Simon Stilgoe, Valerie E Stott

¹Department of Family Medicine Shaikh Khalifa Medical City, Abu Dhabi, United Arab Emirates. purpose@tpg.com.au

Australian Family Physician

|January 15, 2009

Summary

This summary is machine-generated.

Vitamin D plays a crucial role in both bone health and numerous non-musculoskeletal functions. Addressing widespread vitamin D deficiency is essential for public health, utilizing existing communication channels.

Related Experiment Videos

Last Updated: Jun 26, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Area of Science:

Endocrinology
Cell Biology
Public Health

Background:

Vitamin D status is critical for musculoskeletal health.
Emerging evidence highlights vitamin D's non-musculoskeletal roles, including endocrine, autocrine, and cell membrane effects.
These roles encompass kidney and intestinal function, cell differentiation, immune modulation, calcium absorption, and insulin secretion.

Purpose of the Study:

To discuss the multifaceted actions of vitamin D.
To review established sources and methods for measuring vitamin D.
To outline strategies for treating vitamin D deficiency and identify knowledge gaps.

Main Methods:

Literature review and synthesis of current research on vitamin D.
Discussion of clinical management guidelines for vitamin D deficiency.
Exploration of future research directions.

Main Results:

Vitamin D is synthesized in the skin via solar radiation, a process linked to skin cancer and aging.
Breast milk contains low levels of vitamin D in deficient mothers.
Widespread vitamin D deficiency presents a significant public health challenge.

Conclusions:

Vitamin D deficiency is prevalent and impacts multiple physiological systems.
Effective public health strategies can be leveraged to combat vitamin D deficiency.
Further research is needed to fully elucidate vitamin D's functions and optimize clinical management.