Related Experiment Video
Updated: Jun 26, 2026
05:16
Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
Prognostic table for predicting major cardiac events based on J-ACCESS investigation
Kenichi Nakajima1, Tsunehiko Nishimura
1Department of Nuclear Medicine, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, 13-1 Takaramachi, Kanazawa 920-8641, Japan. nakajima@med.kanazawa-u.ac.jp
Annals of Nuclear Medicine
|January 15, 2009
Summary
A new Heart Risk Table estimates cardiac event risk for patients with ischemic heart disease using the J-ACCESS database. This tool aids in predicting major cardiac events, improving patient risk assessment.
Area of Science:
- Cardiology
- Medical Informatics
- Public Health
Background:
- Coronary heart disease (CHD) poses a significant public health challenge.
- Accurate risk stratification is crucial for managing patients with CHD.
- Large-scale prognostic databases offer potential for improved risk estimation.
Purpose of the Study:
- To develop a practical risk assessment tool for major cardiac events in a Japanese population.
- To create a simplified "Heart Risk Table" based on a large prognostic database.
- To predict the 3-year rate of major cardiac events.
Main Methods:
- Utilized the J-ACCESS database (>4,000 patients, 117 hospitals).
- Employed multivariate logistic regression analysis to predict event rates.
- Simplified the logistic regression algorithm to generate user-friendly tables.
Main Results:
- Developed two tables predicting cardiac risk based on age, perfusion score, ejection fraction, and diabetes status.
- Created a relative risk table comparing patients to age-matched controls.
- Demonstrated strong agreement between simplified tables and original logistic regression analysis (P < 0.0001).
Conclusions:
- A validated Heart Risk Table is now available for patients with suspected ischemic heart disease undergoing myocardial perfusion imaging.
- The J-ACCESS database provides a robust foundation for cardiac risk assessment.
- Further validation of this risk assessment tool is recommended.
Related Concept Videos
01:30Acute Coronary Syndrome III: Diagnostic Studies
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
01:30Heart Failure IV: Classification and Diagnostic Evaluation
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
01:26Coronary Artery Disease IV: Preventive Measures
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
01:18Cardiovascular Drugs: Classification based on Therapeutic Indications
Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However, frequent irregular...
01:20Blood Studies for Cardiovascular System I: Cardiac Biomarkers
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...