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Rag proteins regulate amino-acid-induced mTORC1 signalling

Yasemin Sancak1, David M Sabatini

  • 1Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology Department of Biology, Nine Cambridge Center, Cambridge, MA 02142, USA.

Biochemical Society Transactions
|January 16, 2009
PubMed
Summary

Nutrients regulate cell growth by signaling through the mammalian target of rapamycin (mTOR) pathway. Researchers identified the Rag GTPase family as key mediators in this amino acid signaling process.

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