Showing results (1-10 of 275) with videos related to
Sort By:
Pageof 28
Biochemical Society Transactions|January 16, 2009
Rag proteins regulate amino-acid-induced mTORC1 signallingYasemin Sancak, David M SabatiniScience (New York, N.Y.)|November 5, 2011
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPaseRoberto Zoncu, Liron Bar-Peled, Alejo Efeyan, et al.Cell|April 13, 2010
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acidsYasemin Sancak, Liron Bar-Peled, Roberto Zoncu, et al.Science (New York, N.Y.)|May 24, 2008
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1Yasemin Sancak, Timothy R Peterson, Yoav D Shaul, et al.Molecular Cell|March 28, 2007
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinaseYasemin Sancak, Carson C Thoreen, Timothy R Peterson, et al.Cell|May 19, 2009
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survivalTimothy R Peterson, Mathieu Laplante, Carson C Thoreen, et al.Biochemical Society Transactions|March 24, 2023
Beyond the matrix: structural and physiological advancements in mitochondrial calcium signalingMelissa J S MacEwen, Yasemin SancakScience (New York, N.Y.)|November 8, 2005
Tissue-specific TAFs counteract Polycomb to turn on terminal differentiationXin Chen, Mark Hiller, Yasemin Sancak, et al.Proceedings of the National Academy of Sciences of the United States of America|October 29, 2017
Twenty-five years of mTOR: Uncovering the link from nutrients to growthDavid M SabatiniNature Reviews. Cancer|August 18, 2006
mTOR and cancer: insights into a complex relationshipDavid M SabatiniPageof 28