Related Experiment Video
Updated: Jun 26, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
[Vaginal infections in human immunodeficiency virus-infected women]
Paula Matos Oliveira1, Rita Elizabeth Mascarenhas, Suzana Ramos Ferrer
1Programa de Pós-graduação em Medicina e Saúde, Escola Bahiana de Medicina e Saúde Pública, Salvador, BA, Brazil.
Purpose:
to compare the frequency of vulvovaginitis in women infected with human immunodeficiency virus (HIV) with the frequency in non-infected women.
Methods:
a transversal study including 64 HIV infected women and 76 non-infected ones. The frequencies of bacterial vaginosis, candidiasis and trichomoniasis, diagnosed by Amsel's criteria, culture and fresh exam, respectively, were calculated. Chi-square test, Fisher's exact test and multiple regressions to verify the independence of associations were used to analyze the data.
Results:
the vaginal infection was more prevalent in HIV infected patients, as compared to the control group (59.4 versus 28.9%, p<0,001; Odds Ratio=2.7, IC95%=1.33-5.83, p=0.007). Bacterial vaginosis occurred in 26.6% of the positive-HIV women; vaginal candidiasis, in 29.7% and trichomoniasis, in 12.5% of them. All the infections were significantly more frequent in the group of HIV infected women (p=0.04, 0.02 e 0.04, respectively).
Conclusions:
vulvovaginitis is more frequent in HIV infected women.
Related Concept Videos
Sexually Transmitted Infections
Candidiasis
Trichomoniasis
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Genital Herpes
Inhibitors of Virion Maturation and Assembly

