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Related Concept Videos

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Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
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Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...
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Related Experiment Video

Updated: Jun 26, 2026

Experimental Models for Study of Retinal Pigment Epithelial Physiology and Pathophysiology
08:28

Experimental Models for Study of Retinal Pigment Epithelial Physiology and Pathophysiology

Published on: November 6, 2010

[Interferon-beta retinopathy].

M Sallansonnet-Froment1, X Roux, T de Greslan

  • 1Service de neurologie, hôpital d'instruction-des-Armées du Val-de-Grâce, 74, boulevard de Port-Royal, 75230 Paris cedex 05, France. froment.magali@wanadoo.fr

Revue Neurologique
|January 17, 2009
PubMed
Summary
This summary is machine-generated.

Blurred vision in multiple sclerosis patients treated with interferon-beta may indicate interferon-beta retinopathy. This ocular complication, characterized by cotton wool spots, resolved after discontinuing the medication.

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Related Experiment Videos

Last Updated: Jun 26, 2026

Experimental Models for Study of Retinal Pigment Epithelial Physiology and Pathophysiology
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Published on: November 6, 2010

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
09:28

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

Published on: September 16, 2020

Area of Science:

  • Ophthalmology
  • Neurology

Background:

  • Interferon-alpha retinopathy is a known complication of Hepatitis C treatment.
  • Reports of interferon-beta retinopathy in multiple sclerosis patients are less common.

Observation:

  • A 58-year-old male with multiple sclerosis developed blurred vision while on interferon-beta 1a therapy.
  • Fundus examination revealed cotton wool spots, indicative of retinopathy.

Findings:

  • The patient's retinopathy resolved spontaneously two months after discontinuing interferon-beta injections.
  • No other cause for the retinopathy was identified.

Implications:

  • Ophthalmological evaluation, including fundus examination, is recommended for multiple sclerosis patients experiencing new visual symptoms during interferon therapy.
  • Resolution of retinopathy after medication withdrawal supports a diagnosis of interferon-induced retinopathy.