Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Obstructing colorectal carcinomas. Prospective study.

J C Garcia-Valdecasas1, J M Llovera, A M deLacy

  • 1Department of Surgery, Hospital Clinic of Barcelona, University of Barcelona, Spain.

Diseases of the Colon and Rectum
|September 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-term follow-up of the effect of oral dienogest and dienogest/ethinylestradiol treatment on cell-free DNA levels in patients with deep endometriosis.

European journal of medical research·2025
Same author

Dynamics of thrombin generation: Filling the gap between the system pharmacology theory and clinical practice in clinical pharmacology and therapeutics.

Pharmacology research & perspectives·2024
Same author

Serological autoimmune profile of systemic lupus erythematosus in deep and non-deep endometriosis patients.

Journal of reproductive immunology·2023
Same author

Postoperative day one systemic inflammatory response syndrome is a powerful early biomarker of clinically relevant pancreatic fistula.

HPB : the official journal of the International Hepato Pancreato Biliary Association·2022
Same author

Dragon 1 Protocol Manuscript: Training, Accreditation, Implementation and Safety Evaluation of Portal and Hepatic Vein Embolization (PVE/HVE) to Accelerate Future Liver Remnant (FLR) Hypertrophy.

Cardiovascular and interventional radiology·2022
Same author

Prevention of venous thromboembolism in hematologic neoplasms: an expert consensus from SEHH-SETH.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2021
Same journal

A Penny for Your Thoughts.

Diseases of the colon and rectum·2026
Same journal

June 2026 Translations.

Diseases of the colon and rectum·2026
Same journal

Selected Abstracts.

Diseases of the colon and rectum·2026
Same journal

Recurrence After Rectopexy: Insights From Magnetic Resonance Defecography.

Diseases of the colon and rectum·2026
Same journal

Risk of Metabolic Disease After Right- vs Left-Sided Colectomy for Colon Cancer: A Nationwide Cohort Study.

Diseases of the colon and rectum·2026
Same journal

Sexual Distress Is Common in Long Term Follow-up After Pelvic Pouch for Ulcerative Colitis: A Cross-Sectional Study.

Diseases of the colon and rectum·2026
See all related articles

Colorectal cancer causing intestinal obstruction often presents with advanced tumors. Tumor stage, not obstruction itself, is the key predictor of outcomes in patients undergoing surgery.

Area of Science:

  • Colorectal Surgery
  • Surgical Oncology
  • Gastroenterology

Background:

  • Intestinal obstruction from colonic carcinoma is a common cause of acute abdominal pain.
  • Patient outcomes can vary significantly based on surgical approach and tumor characteristics.

Purpose of the Study:

  • To identify prognostic factors influencing outcomes in patients with colonic carcinoma presenting with intestinal obstruction (OG) versus elective surgery (EG).
  • To compare curative resection rates, morbidity, mortality, and tumor staging between OG and EG groups.

Main Methods:

  • Prospective study including 188 patients with colorectal cancer from September 1984 to March 1988.
  • Comparison of outcomes between 53 patients with obstruction (OG) and 135 patients undergoing elective surgery (EG).

Related Experiment Videos

  • Multivariate analysis using a proportional hazards model to determine independent prognostic factors.

    • Main Results:

    • Curative resection rates were significantly higher in the elective group (EG) (P = 0.029).
    • Tumor staging was significantly more advanced in the obstruction group (OG) (P = 0.026).
    • Multivariate analysis identified tumor staging as the sole independent prognostic factor, overshadowing obstruction status.

    Conclusions:

    • Obstructing colon carcinomas are frequently more locally advanced.
    • Advanced tumor stage, rather than the obstruction itself, is the primary determinant of a worse long-term prognosis in these patients.