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Updated: Jun 26, 2026

Sperm Collection of Differential Quality Using Density Gradient Centrifugation
Published on: November 29, 2018
[Interference of age on semen quality].
Marcelo Borges Cavalcante1, Marcelo de Pontes Rocha, Marjorie Luzia Custódio Mota Dias
1Centro de Reprodução Assistida do Ceará, Fortaleza, CE, Brazil. cavalcantemb@secrel.com.br
Age impacts ejaculated semen volume, decreasing it as men get older. However, age does not significantly affect sperm concentration, motility, or morphology in men undergoing fertility assessments.
Area of Science:
- Reproductive Medicine
- Andrology
- Human Reproduction Research
Context:
- Conjugal infertility affects numerous couples globally.
- Semen quality is a critical factor in male fertility.
- Understanding age-related changes in semen parameters is vital for reproductive health assessments.
Purpose:
- To investigate the relationship between male age and semen quality parameters.
- To evaluate how age influences seminal volume, sperm concentration, motility, and morphology.
- To assess the impact of age in men seeking fertility treatment.
Summary:
- This retrospective study analyzed 531 semen analyses from men with infertility.
- Semen parameters including volume, concentration, motility, and morphology were assessed.
- Older men with hypospermia (low semen volume) were identified, with significantly higher average age compared to normospermic individuals.
Impact:
- Age is inversely proportional to ejaculated semen volume.
- Sperm concentration, motility, and morphology are not significantly influenced by age.
- Findings contribute to understanding male reproductive aging and fertility evaluations.
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