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Updated: Jun 26, 2026
11:04
An In-House-Built and Light-Emitting-Diode-Based Photodynamic Therapy Device for Enhancing Verteporfin Cytotoxicity in a 2D Cell Culture Model
Published on: January 13, 2023
Drug delivery systems for photodynamic therapy
Ryan F Donnelly1, Paul A McCarron, David Woolfson
1School of Pharmacy, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL, UK. r.donnelly@qub.ac.uk
Recent Patents on Drug Delivery & Formulation
|January 20, 2009
Summary
Photodynamic therapy (PDT) innovations focus on novel drug delivery systems. Recent patents reveal advancements in photosensitizer delivery, crucial for enhancing PDT
Area of Science:
- Biomedical Engineering
- Pharmaceutical Sciences
- Photochemistry
Background:
- Photodynamic therapy (PDT) utilizes photosensitizing drugs and light for targeted cell destruction.
- PDT is transitioning from experimental to established clinical practice.
- Limited pharmaceutical formulation development has historically constrained PDT's full potential.
Purpose of the Study:
- To review innovations in drug delivery systems for photodynamic therapy.
- To highlight advancements disclosed in recent patent literature.
- To emphasize the importance of effective photosensitizer delivery for clinical PDT.
Main Methods:
- Analysis of recent patent literature concerning photodynamic therapy drug delivery.
- Identification of novel approaches in photosensitizer formulation and administration.
- Review of technological advancements in photosensitizer delivery systems.
Main Results:
- Significant innovations in photosensitizer delivery systems are emerging.
- Patents demonstrate diverse strategies for improving drug targeting and efficacy.
- Advancements address challenges in photosensitizer stability, solubility, and targeted release.
Conclusions:
- Optimized drug delivery systems are critical for realizing the full clinical potential of PDT.
- Recent patent literature indicates a growing focus on innovative PDT formulations.
- Further development in photosensitizer delivery is essential for advancing PDT applications.
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