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Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Malignant mesenterial mesothelioma in stroke patients
Dewa Gde Agung Budiyasa1, I Dewa Nyoman Wibawa
1Department of Internal Medicine Udayana University-Sanglah General Hospital. Jalan Kesehatan 1, 80229 Denpasar, Bali. srimartini@hotmail.com
Abstract:
Mesothel is the cell lining of serosal surface of the pleura, peritoneum, pericardium, and testis. Malignant mesothelioma is a highly aggressive tumor from mesothel that has a tendency to grow rapidly and invade locally. Although the incidence of malignant mesenterial mesothelioma is not so high, the case fatality rate is very high. The aim of this case report is to report the rare and difficult case with several complications. A Balinese man, 64 years old, came with chief complaint of weakness, abdominal enlargement, and nausea, with history of previous liver disease. On physical examination were found a decrease of conciousness, subfebrile, abdominal distension, ascites, negative traube space, and paralysis of the left side of the body. Laboratory examination results showed leukocytosis, hypochromic-micrositic anemia, trombocytosis, hypoalbuminemia, increase of alkaline phosphatase, and mild hyponatremia. Abdominal USG showed intraperitoneal mass which some of them attach to abdominal wall, possibly from mesenterium and ascites, esophagogastroduodenoscopy (EGD) revealed reflux esofagitis and anthral erossive gastritis, skull CT scan showed small infarction at left parietal medulla and right basal ganglia, cytology showed spreaded and grouped mesothel with reactive lymphocyte and amorph back ground. FNAB result showed malignant mesothelioma, and normal colonoscopy. Based on the above data, the diagnoses were malignant mesenterial mesothelioma, reflux esofagitis and anthral erossive gastritis, and non hemorrhagic stroke. Malignant mesenterial mesothelioma should be considered in patient with the combination of unexplained ascites and abdominal pain. Although the result of treatment is very disappointing, the patient had to be treated optimally to increase quality of life.
Insights
This case report details a rare instance of malignant mesenteric mesothelioma in a 64-year-old man, presenting with ascites and neurological deficits. The aggressive tumor led to a high fatality rate despite optimal treatment efforts.
Area of Science:
- Oncology
- Gastroenterology
- Neurology
Background:
- Malignant mesothelioma is an aggressive tumor originating from mesothelial cells, with malignant mesenteric mesothelioma being a rare subtype.
- The case involves a 64-year-old Balinese man with a history of liver disease, presenting with complex symptoms.
Observation:
- The patient exhibited weakness, abdominal enlargement, nausea, decreased consciousness, ascites, and left-sided paralysis.
- Laboratory findings included leukocytosis, anemia, thrombocytosis, hypoalbuminemia, elevated alkaline phosphatase, and mild hyponatremia.
- Imaging revealed an intraperitoneal mass, ascites, and cerebral infarction; endoscopy showed esophagitis and gastritis.
Findings:
- Cytology and Fine Needle Aspiration Biopsy (FNAB) confirmed malignant mesothelioma.
- The final diagnoses included malignant mesenteric mesothelioma, reflux esophagitis, anthral erosive gastritis, and non-hemorrhagic stroke.
Implications:
- Malignant mesenteric mesothelioma should be considered in patients with unexplained ascites and abdominal pain.
- Optimal treatment is crucial for improving the quality of life, even in cases with a poor prognosis.

