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A Catheter-Related Candida albicans Infection Model in Mouse
Published on: March 22, 2024
Candida albicans gene expression in an in vivo infection model
1Department of Microbiology, East Tennessee State University, James H Quillen College of Medicine, Johnson City, TN, USA.
Methods in Molecular Biology (Clifton, N.J.)
|January 20, 2009
Abstract:
A general procedure is described for the analysis of gene expression of Candida albicans cultured in a mouse infection model. This technique involves first infecting mice with Candida and subsequently harvesting blood and other tissue at specific time points during infection. The tissues are homogenized and the infecting Candida isolated. Finally, RNA is extracted from recovered Candida cells and subjected to microarray analysis.
