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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.

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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Milia complicating bullous polymorphic light eruption.

Cristina Bulai Livideanu1, Alfred Ammoury, Roland Viraben

  • 1Department of Dermatology, Purpan University Hospital, Toulouse, France. livideanu.c@chu-toulouse.fr

Photodermatology, Photoimmunology & Photomedicine
|January 21, 2009
PubMed
Summary

Polymorphic light eruption (PLE), a common photosensitivity disorder, typically causes itchy rashes after sun exposure. This case highlights a rare complication of bullous PLE with milia, an association not previously documented in medical literature.

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Published on: October 12, 2012

Area of Science:

  • Dermatology
  • Photodermatology
  • Cutaneous Medicine

Background:

  • Polymorphic light eruption (PLE) is the most prevalent photosensitivity disorder.
  • PLE commonly presents as pruritic papular or vesicular rashes on sun-exposed skin during warmer months.
  • The pathogenesis involves immune responses to UV radiation, leading to various clinical presentations.

Observation:

  • A unique case of bullous PLE was observed.
  • This specific presentation was complicated by the development of milia.
  • Milia formation is typically associated with epithelial proliferative tendencies post-injury, sometimes seen in subepidermal blistering.

Findings:

  • This report details an original case of bullous polymorphic light eruption (PLE).
  • The bullous PLE was complicated by the occurrence of milia.
  • This specific association between bullous PLE and milia has not been previously documented in scientific literature.

Implications:

  • This case expands the known clinical spectrum of polymorphic light eruption (PLE).
  • It suggests a potential link between subepidermal blistering in PLE and subsequent milia formation.
  • Further research may elucidate the mechanisms underlying this rare complication and inform clinical management.