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Updated: Jun 26, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Evolution of midface rejuvenation
Robert J DeFatta1, Edwin F Williams
1Department of Facial Plastic and Reconstructive Surgery, Williams Center, Plastic Surgery Specialists, 1072 Troy Schenectady Rd, Latham, NY 12110, USA.
Abstract:
Age is the most significant factor contributing to the overall change in the appearance of an individual's facial features over time. This gradual process of structural weakening of the face begins during the third decade and continues to worsen during the remainder of an individual's lifetime. In this article we discuss how the approach to midface rejuvenation has evolved over time owing to our increased understanding of the aging process. In addition, we discuss specific techniques that we employ that have helped us achieve more natural and lasting results.
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