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Updated: Jun 26, 2026

Identification of Fatty Acids in Bacillus cereus
Published on: December 5, 2016
[New regulatory and signal functions for myristic acid]
Erwan Beauchamp1, Vincent Rioux, Philippe Legrand
1Laboratoire de Biochimie-Nutrition Humaine, Agrocampus Rennes-INRA USC 2012, 65, rue de Saint-Brieuc, 35042 Rennes Cedex, France.
Abstract:
Myristic acid is a 14 carbon saturated fatty acid, which is mostly found in milk fat. In industrialized countries, its excessive consumption is correlated with an increase in plasma cholesterol and mortality due to cardiovascular diseases. Nevertheless, one feature of this fatty acid is its ability to acylate proteins, a reaction which is called N-terminal myristoylation. This article describes various examples of important cellular regulations where the intervention of myristic acid is proven. Modulations of the cellular concentration of this fatty acid and its associated myristoylation function might be used as regulators of these metabolic pathways.
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