Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Patient triggered ventilation in chronically ventilator-dependent infants.

M F Hird1, A Greenough

  • 1Department of Child Health, King's College Hospital, London, United Kingdom.

European Journal of Pediatrics
|August 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Non-invasive carbon dioxide monitoring in the UK: a survey of practice within neonatal intensive care.

Anaesthesia·2021
Same author

Review finds insufficient evidence to support the routine use of heated, humidified high-flow nasal cannula use in neonates.

Acta paediatrica (Oslo, Norway : 1992)·2014
Same author

Airways obstruction and pulmonary capillary blood volume in children with sickle cell disease.

Pediatric pulmonology·2013
Same author

Predictors of neonatal morbidity in fetuses with severe isolated congenital diaphragmatic hernia undergoing fetoscopic tracheal occlusion.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2013
Same author

Antenatal and postnatal management of congenital cystic adenomatoid malformation.

Paediatric respiratory reviews·2012
Same author

Congenital diaphragmatic hernia.

The European respiratory journal·2011

Patient triggered ventilation (PTV) using an airway pressure trigger infrequently supports infants needing long-term mechanical ventilation. Most infants failed to maintain PTV due to inadequate respiratory efforts and asynchrony.

Area of Science:

  • Neonatal Medicine
  • Pediatric Critical Care
  • Respiratory Physiology

Background:

  • Mechanical ventilation is essential for preterm infants with respiratory failure.
  • Prolonged ventilator dependence poses significant challenges in neonatal care.
  • Patient triggered ventilation (PTV) aims to improve synchrony between infant and ventilator.

Purpose of the Study:

  • To evaluate the efficacy of patient triggered ventilation (PTV) with an airway pressure trigger in ventilator-dependent preterm infants.
  • To identify factors predicting successful PTV use and reasons for failure.

Main Methods:

  • A cohort of 16 preterm infants requiring mechanical ventilation beyond the first week of life were studied.
  • PTV was delivered using a ventilator with an airway pressure trigger.

Related Experiment Videos

  • Infant-ventilator synchrony and trigger delay were assessed.

    • Main Results:

    • PTV was successfully maintained until extubation in only 3 out of 16 infants.
    • Failure occurred in 13 infants within a median of 1 hour, often due to inadequate respiratory efforts or asynchrony.
    • Successful PTV use was associated with older infants, greater maturity, higher birth weight, and shorter trigger delay.

    Conclusions:

    • Airway pressure-triggered PTV is infrequently successful in providing adequate respiratory support for chronically ventilator-dependent preterm infants.
    • Infant-ventilator asynchrony within the first hour is a predictor of PTV failure.