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[Andrological testosterone replacement therapy]
U Paasch1, H-J Glander, J-U Stolzenburg
1Weiterbildungszentrum der European Academy of Andrology, Campus Leipzig, Klinik für Dermatologie, Venerologie und Allergologie der Universität Leipzig, Philipp-Rosenthal-Strasse 23-25, 04103 Leipzig. uwe.paasch@medizin.uni-leipzig.de
Der Urologe. Ausg. A
|January 22, 2009
Summary
Male hypogonadism, or low testosterone, affects many men but is underdiagnosed and undertreated. Testosterone replacement therapy is available but requires careful screening due to potential risks.
Area of Science:
- Endocrinology
- Andrology
- Men's Health
Context:
- Male hypogonadism is a condition of decreased testicular function, primarily testosterone deficiency.
- Prevalence increases with age but can occur at any life stage.
- Clinical symptoms manifest due to testosterone deficiency, yet only 10% receive adequate treatment.
Purpose:
- To highlight the characteristics and prevalence of male hypogonadism.
- To discuss available testosterone replacement therapies.
- To emphasize the importance of screening and contraindications for treatment.
Summary:
- Male hypogonadism involves reduced testosterone production, leading to various symptoms.
- Various testosterone formulations exist, including intramuscular, transcutaneous, sublingual, and oral.
- Treatment is contraindicated in specific conditions like prostate cancer, severe heart failure, and untreated sleep apnea.
Impact:
- Increases awareness of male hypogonadism and its underdiagnosis.
- Provides an overview of treatment options and their administration routes.
- Stresses the necessity of clinical and laboratory screening for safe and effective testosterone substitution therapy.
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