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Updated: Jun 26, 2026

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly
Published on: April 17, 2014
Self-assembly nano-structure of type I collagen adsorbed on Gemini surfactant LB monolayers
Shouhong Xu1, Aiping Liu, Qibin Chen
1Lab for Advanced Materials and Department of Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
Abstract:
The self-assembly nano-structures of type I collagen adsorbed on anionic Gemini surfactant LB monolayer were observed by using atomic force microscopy (AFM) images. It was found that the adsorption behavior and self-assembly structure of collagen could be controlled by the concentration of the collagen solution, adsorption interval and the properties of substrates. With the increase of the adsorption interval and concentration of collagen, the strands size of collagen changed. The self-assembly structures of collagen were also influenced by the interaction between collagen molecules and Gemini surfactant monolayer substrates. Finally, the adsorption behaviors of collagen molecules on cationic Gemini monolayer were compared with those on anionic Gemini monolayer.
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