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Updated: Jun 26, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Intraarterial therapy for acute ischemic strokes.
Jeffrey G Belisle1, Vance E McCollom, Timothy L Tytle
1University of Oklahoma College of Medicine, Oklahoma City, Oklahoma, USA.
Intraarterial stroke therapy for acute ischemic stroke proved safe and feasible in a community setting. This treatment approach showed promising outcomes, including improved patient function and successful recanalization rates.
Area of Science:
- Neurology
- Interventional Radiology
- Vascular Medicine
Background:
- Acute ischemic stroke requires timely intervention.
- Intraarterial therapies offer targeted treatment options.
Purpose of the Study:
- To assess the safety and feasibility of intraarterial stroke therapy.
- To evaluate outcomes of intraarterial interventions for acute ischemic stroke at a community medical center.
Main Methods:
- Retrospective analysis of 83 consecutive stroke patients treated between June 2004 and April 2007.
- Intraarterial therapies included thrombolytics, vasodilators, mechanical clot retrieval, stents, and angioplasty within 6 hours of symptom onset.
- Outcomes measured: NIHSS, modified Rankin Scale (mRS) at 90 days, recanalization, hemorrhage, and mortality.
Main Results:
- Median NIHSS improved from 17 to 5 post-therapy.
- 51% of patients achieved an mRS score of 2 or less at 90 days.
- Recanalization rate was 76%, with 6% experiencing symptomatic intracranial hemorrhage and 22% 90-day mortality.
Conclusions:
- Intraarterial therapy for acute ischemic stroke is feasible in a community hospital setting.
- The approach demonstrated encouraging safety and efficacy.
- Results support the use of intraarterial interventions for acute ischemic stroke in community medical centers.
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